Explore the body map
Tap a body area or a topic to see how tocotrienols may support it, and how far the evidence has travelled: from cells, to animals, to people.
Dose ranges used in published trials
Educational reference only. These describe study protocols, not recommendations. Always consult a qualified healthcare professional.
| Research area | Daily dose in trials | Duration | Common form | Evidence |
|---|---|---|---|---|
| Lipid profile | 100–300 mg | 8–16 weeks | δ/γ-rich | Moderate |
| Liver fat (NAFLD) | 300–600 mg | 12–48 weeks | Palm TRF | Moderate |
| Cognitive / white matter | 200–400 mg | up to 2 years | Mixed TRF | Emerging |
| Bone density | 100–600 mg | 12–24 weeks | Annatto δ | Emerging |
| Skin & UV stress | Topical / 100–200 mg | 4–12 weeks | α/γ mix | Early |
Common questions
Is tocotrienol the same as vitamin E?
Tocotrienols are one half of the vitamin E family. “Vitamin E” on most labels means alpha-tocopherol only; tocotrienols are rarely included.
Can I get enough from food?
Typical diets give only a few milligrams a day. The amounts used in research (100–300 mg) come from concentrated annatto, palm or rice-bran extracts.
Does tocopherol block tocotrienol?
High intakes of alpha-tocopherol can reduce tocotrienol absorption and tissue levels, which is why tocopherol-free annatto extracts are often used in trials.
When is the best time to take it?
Tocotrienols are fat-soluble, so absorption improves when taken with a meal that contains fat.
Are there safety concerns?
Human trials up to 400–800 mg/day have generally reported good tolerance. Anyone on blood thinners or with a medical condition should speak to a clinician first.
Educational disclaimer: This site summarises published research for learning purposes. It is not medical advice and does not diagnose, treat or prevent any disease.
NextKnowledge Hub: the studies behind the map